Yu is a young boy suddenly bestowed with the powers of the Amazing Spider-Man! Can he find his courage in time to save the day?

Your Friendly Neighborhood Spider-Man is branching out!

Welcome to Ohakama City, Japan. Yu, a timid boy who loves to draw manga, is attacked by a villain, only to be rescued by the super hero known as Spider-Man! Despite being defeated, the villain activates a device that merges Yu and Spider-Man together.

Ohakama City is under attack! Facing an alliance between several villains--not to mention the Green Goblin himself lurking around in the shadows--Spider-Man Kizuna is in for the fight of his life. It's too much for any single hero to handle, and even a double-hero like Spider-Man Kizuna will have a hard time! But Spider-Man and Yu aren't alone...they have friends, too. Friends with powers, and a burning desire to protect Ohakama City from evil. The Kizuna Kids are here, and they've got Spider-Man Kizuna's back!